Semaglutide as a drug for obese adults was discovered by scientists to help with weight loss as part of a new experimental study.
For the first time, this study emphasized that medicine alone can accomplish such a feat.
But despite new discoveries, a healthy lifestyle is still fundamental.
Medicine and lifestyle
(Photo: ANDRES LARROVERE / AFP via Getty Images)
The study, published in The New England Journal of Medicine on March 18, acknowledged that obesity is a global health problem and leads to various types of illnesses such as insulin resistance, hypertension, diabetes and cardiovascular disease. I did. As frequent hospitalizations.
With only a few pharmacological options, the study considered lifestyle changes alone to be challenging, but the associated medications made all the differences between clinical trials.
Research scientists enrolled 1,961 adults with a body mass index (BMI) greater than 30 and were classified as obese.
Subjects were part of a double-blind study and were divided into two groups, a semaglutide group and a placebo group.
As a neutralizing factor, both groups do not have a recorded diagnosis of diabetes. They were also given lifestyle interventions to help them in their physical activity, calorie reduction, and other means to help them lose weight.
However, there are differences when it comes to issuing obesity medicines.
The semaglutide group received weekly semaglutide treatment for 68 weeks, while the placebo group received fake but harmless tablets for psychological motivation of subjects during the same study period.
As a result, adults in the semaglutide group achieved more weight loss than the other groups.
Read again: Eating white bread increases the risk of obesity
obesity
Obesity is a health condition in which fat accumulation is significantly higher than normal, based on the individual’s age, gender, and body size.
According to the World Health Organization (WHO), obesity has already reached an epidemic rate worldwide, killing more than 2.8 million people each year.
Since 1975, obesity around the world has tripled. In 2016, more than 1.9 billion adults were overweight. Those 650 million were obese.
WHO has observed that obesity was once thought to be a sign of high-income or First World countries.
Nevertheless, it already exists in low- and middle-income countries, also known as developing countries.
BMI
WHO emphasized that BMI is the most useful measure to determine if a person is normal weight, overweight, or obese.
The following BMI categories and analogies are:
- A BMI of 30 or higher means that a person is obese
- BMI over 25 is overweight
- People with a BMI of 24.9 or less have a normal weight
Complications and death
The health complications of obesity result from a chain reaction from a potential non-communicable disease due to increased vulnerabilities in people who are currently obese.
According to the US Centers for Disease Control and Prevention (CDC), obesity-related conditions include heart disease, stroke, and certain types of cancer.
Still, the CDC states that premature death due to complications and obesity can be prevented.
Related article: It’s all in the gene: obesity can be inherited from parents
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